Meredith: [voiceover] In the OR, time loses all meaning. In the midst of sutures, and saving lives... the clock ceases to matter. 15 minutes... 15 hours ā€” inside the OR, the best surgeons make time fly. Outside the OR, however, time takes pleasure in kicking our asses. For even the strongest of us it seems to play tricks. Slowing down... hovering... until it freezes. Leaving us stuck in a moment ā€” unable to move in one direction or the other.

Meredith: [pause, glances around] Why are you all looking at me?
Cristina: Well, this is familiar territory for you.
Meredith: There is nothing familiar abut this! Unfamiliar! Denny died. The man she loves, died.
Cristina: Yeah, but you're all dark and twisty inside.
Meredith: I am not dark and twisty!
Cristina: What, with the Alzheimers thing and the father you don't talk to.
Alex: And the tequila thing and the inappropriate men thing.
George: You are dark and twisty inside, Meredith, and now Izzie is dark and twisty inside.
Meredith: So all of a sudden I'm the president of people with crappy lives?

Meredith: Denny died. Burke got shot. Let's just have a little perspective and realize that what I did was a tiny, slightly small...
Cristina: Oh, whatever, just spit it out!
Meredith: I lost my panties, last night.

Cristina: You and McDreamy did the Nasty Nasty?
[Meredith glares at her]
Meredith: Cristina!
Cristina: I'm not judging! I'm just trying to wrap my mind around it. I mean, you are with Finn and he's with Addison.
Meredith: He's married to Addison.
Cristina: YEAH! [pause] Well what did Derek say?
Meredith: He said "Meredith what does this mean?"
Cristina: Ugh! Ok! He has sex with you and he's standing there all McGuilty and all he can say is "Oh, What does this mean?" [pause] What does this mean?

Callie: [to Finn] Four years of high school, four years of college, four years of med school : by the time we graduate we're in our late twenties and we've never done anything except go to school and think about science. Time stops. We're socially retarded. Ha, I mean, look at me, I'm in love with a guy who won't say he loves me back and here I am, in his kitchen, just hoping he comes home and notices me. I'm a total freak. I'm that girl, who sits in the back of the class and eats her hair. And Meredith, shes seventeen years old, we're all seventeen years old. This is high school with scalpels, Finn.

Izzie: I feel like I'm moving in slow motion and everything around me is moving so fast... and I just want to go back to when things were normal, when I wasn't poor Izzie laying on the bathroom floor in her prom dress with her... her dead fiancee. But I am. So I can't. And...I'm just stuck... And there's all this pressure cause everyones hovering around waiting for me to do something or say something or flip out or yell or cry some more. And I'm happy to play my part. I'm happy to say the lines and do whatever it is I'm supposed to be doing if it would make everyone feel more comfortable. But I don't... I don't know how to do this. I don't know how to be this person. I don't know who this person is.
Meredith: Izzie...
Izzie: How did this happen? Why did we end up here? Why am I alone? Where's Denny?
Meredith: You're not alone, Iz.

George: That woman died. She actually died.
Derek: Doesn't mean we will.
George: Is it hot in here?
Derek: (Dismissively) No.
George: Then why am I sweating?
Derek: Because you're pacing.
George: My pulse is rapid.
Derek: Because you're still pacing.
George: (puts hand to his forehead) Feel me.
Derek: No, I'm not gonna feel you.
George: Seriously.
Derek: Seriously, no.

George: You know what? You're an ass. You've lived! You've done things. And you've got the hair. And the hot wife, and the beautiful ex-mistress who's pining for you...
Derek: She's pining for me?
George: You've lived! If you die, who cares... If I die, what? This is IT? Callie told me she loved me, I just sat there. I wasn't ready, but now I'm gonna die, and I'll never get the chance to say I love you back.
Derek: Do you? Do you love her?
George: Maybe. Eventually, I could. One day...soonish...
Derek: Soonish. I will love you soonish? [laughs]

Cristina: Don't ever die.
Burke: I'll do my best.

Derek: [to Meredith] Iā€™m in love with you. Iā€™ve been in love you with you forever. Iā€™m a little late- I know Iā€™m a little late in telling you that. I just, I just want you take your time. Take all the time you need because you have a choice to make. And when I had a choice to makeā€¦I chose wrong.

Meredith: [voiceover] Time flies. Time waits for no man. Time heals all wounds. All any of us wants is more time. Time to stand up. Time to grow up. Time to let go. Time.

Meredith: [voiceover] At any given moment, the brain has 14 billion neurons firing at a speed of 450 miles per hour. We donā€™t have control over most of them. When we get a chill...goose bumps. When we get excited...adrenaline. The body naturally follows its impulses, which I think is part of what makes it so hard for us to control ours. Of course, sometimes we have impulses we would rather not control, that we later wish we had.

Cristina: Benjamin O'Leary, 32, in for the removal of a brain tumor that's pressing on his temporal frontal lobe. Clearly it's effecting his impulse control.
Benjamin: It makes me say everything I think. Which apparently is annoying. This doctor looks annoyed anyway. Although it's hard to tell cause she always has a pinched uptight look on her face. Am I annoying you?
Cristina: It's fine.
Ruthie: You can't say it's fine. He doesn't preceive sarcasm or irony. If he's annoying you, you have to tell him.
Benjamin: Maybe I'm not annoying her Ruthie.
Cristina: No, you are.
Bailey: Doctor Yang!
Cristina: He asked!
Derek: Okay Benjamin, Doctor Yang, as pinched and annoyed as she might be, is going to prep you for surgery today. Do you have any questions for me?
Benjamin: [about Meredith] Is that blonde your girlfriend? 'Cause the way you keep looking at her, you might as well just mount her right here, right now. [Derek and the interns are trying not to laugh.] I'm sorry was I rude?

Bailey: [angry] I'm proud of you all. You make me proud. You reflect on me well. Grey, if you think you can keep your clothes on long enough to follow up the labs I will appreciate it.
Alex: The pit? Iā€™m off gynie?
Bailey: Doctor Montgomery-Shepherd is out sick. You can cover the pit or you canā€¦ [notices the bulletin board] You can tell me who's damn panties are on the bulletin board! [Alex and George laugh]
Cristina: [whispers to Meredith] Yours?
Bailey: This is a hospital people, serious work happens here. We save lives here--[to Alex] Oh, something funny? [Alex shakes his head] Whose are these?
Meredith: [whispers to Cristina] This is bad, this isn't good.
Cristina: [whispers to Meredith] You better claim them. She thinks they are mine. Claim them!
Meredith: [whispers to Cristina] No!
Bailey: [looking at Meredith and Cristina] I know it's one of you. It's always one of mine. Always. So tell me, which one of you left your damn drawers on my surgical floor?!

Bailey: All four of you, do not make me regret setting you loose in this hospital. Please do not make me regret letting you loose in this hospital. O'Malley, what do I mean by this?
George: You mean check with you before we cut any wires or steal any hearts?

Alex: So, you and O'Malley, huh? How'd that happen?
Callie: I don't know, you're a surgeon, how'd that happen?

Cristina: His mother rivals my mother and that's saying something. Both of them, dark and evil.
Meredith: I'm missing dirty stripper Cristina. She was fun and less angry.
Cristina: Next time she even looks at me sideways, Iā€™m telling her what I think. She wants to call me a racist. Yeah, okay? Iā€™ll call her a sexist. Change my career after Iā€™m married. What is this, 1953? If she comes at me, Iā€™m going there.
Meredith: I think you should. I think we should all just go there. You know, tell the truth, spit it out, go with your gut, follow your instincts.
Cristina: I miss philandering whore Meredith. She was trashy, and much less idyllic.

Addison: Dr. Stevens!
Izzie: Please don't call me doctor.
Addison: Oookay, please don't call me Mrs. Shepherd! Haaaa! That's funny.
Izzie: She's drunk.
Joe: This is true.
Addison: Did you know about the slutty sex your slutty friend had with my super slutty husband?
Izzie: You should have a muffin. They're really good and they help you.
Addison: I may be beyond help.
Izzie: Yeah, me too.

Meredith: [voiceover] The body is a slave to its impulses. But the thing that makes us human is what we can control. After the storm, after the rush, after the heat of the moment has passed, we can cool off and clean up the messes we made. We can try to let go of what was. Then again...

Meredith: [voiceover] Surgeons usually fantasize about wild and improbable surgeries. Someone collapses in a restaurant, you splice them open with a butter knife, replace a valve with a hollowed out stick of carrotā€” but every now and then some other kind of fantasy slips in. Most of our fantasies resolve when we wake, vanished to the back of our mind, but sometimes we're sure if we try hard enoughā€” we can live the dream.